Substance
ID:357480
Names and Identifiers
IUPAC name
1H-indol-5-amine
IUPAC Traditional name
5-aminoindole
Synonyms
5-Aminoindole5-氨基吲哚5-IndolamineNSC 614525-吲哚胺
Registration numbers
Beilstein Number
CAS Number
MDL Number
PubChem SID
EC Number
Properties
Physical Property
Melting Point
133-136 °C
131-133 °C (dec.)(lit.)
Safety Information
GHS Hazard statements
H302-H315-H319-H335
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
26
GHS Signal Word
Warning
GHS Precautionary statements
P261-P305+P351+P338
German water hazard class
3
MSDS Link
Risk Statements
22-36/37/38
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
European Hazard Symbols
Harmful (Xn)Product Information
Empirical Formula (Hill Notation)
C8H8N2
Grade
technical
Purity
≥95.0% (NT)
Molecule Details
Application
Reactant for preparation of:
• Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP1
• Cytotoxic and antimitotic agents2
• Insulin-like growth factor 1 receptor inhibitors3
• Antitumoral agents4
• Factor Xa inhibitor5
• Potential antivascular agents6
• Gli1-mediated transcription in the Hedgehog pathway7
• Inhibitors of receptor tyrosine kinase with antiangiogenic effects8
• PKCθ inhibitors9
• HIV protease inhibitors10
Reactant for preparation of:
• Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP1
• Cytotoxic and antimitotic agents2
• Insulin-like growth factor 1 receptor inhibitors3
• Antitumoral agents4
• Factor Xa inhibitor5
• Potential antivascular agents6
• Gli1-mediated transcription in the Hedgehog pathway7
• Inhibitors of receptor tyrosine kinase with antiangiogenic effects8
• PKCθ inhibitors9
• HIV protease inhibitors10
Molecular Spectra
No Data Available
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References
No Data Available
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