Substance
ID:357354
Names and Identifiers
IUPAC name
2-(1H-imidazol-4-yl)ethan-1-amine
IUPAC Traditional name
histamine
Synonyms
组胺2-(4-咪唑基)乙胺Histamine2-(4-Imidazolyl)ethylamine
Registration numbers
PubChem SID
EC Number
Beilstein Number
CAS Number
MDL Number
Properties
Safety Information
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Risk Statements
22-36/37/38-42/43
UN Number
2811
European Hazard Symbols
Harmful (Xn)RTECS
MS1050000
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
MSDS Link
RID/ADR
UN 2811 6.1/PG 3
Safety Statements
22-26-36/37
Storage Temperature
-20°C
Packing Group
3
GHS Precautionary statements
P261-P280-P301+P310-P305+P351+P338-P342+P311
GHS Signal Word
Danger
GHS Hazard statements
H301-H315-H317-H319-H334-H335
Hazard Class
6.1
German water hazard class
3
Physical Property
Melting Point
83-84 °C(lit.)
~84 °C
Boiling Point
167 °C/0.8 mmHg(lit.)
Product Information
Purity
≥97.0% (NT)
Empirical Formula (Hill Notation)
C5H9N3
Pharmacology Properties
Gene Information
human ... CA1(759), CA2(760), HRH1(3269), HRH2(3274), HRH3(11255), HRH4(59340)rat ... Hrh1(24448), Hrh3(85268)
Molecule Details
Biochem/physiol Actions
Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2 activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.
Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2 activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data