Substance
ID:356795
Names and Identifiers
IUPAC name
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate
IUPAC Traditional name
forskolin
Synonyms
Coleonol7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-oneForskolinColforsin
Registration numbers
CAS Number
MDL Number
EC Number
Beilstein Number
Properties
Product Information
Purity
≥98.0% (TLC)
Empirical Formula (Hill Notation)
C22H34O7
Biological Source
from Coleus forskohlii
Safety Information
GHS Hazard statements
H312
European Hazard Symbols
Harmful (Xn)Safety Statements
22-36/37
GHS Signal Word
Warning
Storage Temperature
-20°C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
21
RTECS
QL6150000
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Precautionary statements
P280
German water hazard class
3
MSDS Link
Molecule Details
Biochem/physiol Actions
Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase.
Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase.
Molecular Spectra
No Data Available
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References
No Data Available
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