Substance

ID:356118

Tetracycline hydrochloride

Names and Identifiers
IUPAC name
(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
IUPAC Traditional name
tetracycline hydrochloride
Synonyms
四环素 盐酸盐Tetracycline hydrochloride
Registration numbers
EC Number
CAS Number
MDL Number
Beilstein Number
Properties
Physical Property
Melting Point
215-220 °C (dec.)
220-223 °C(lit.)
Optical Rotation
[α]20/D -245±9°, c = 1% in methanol
Safety Information
GHS Pictograms
GHS07
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Precautionary statements
P261-P305+P351+P338
GHS Signal Word
Warning
Risk Statements
36/37/38
Storage Temperature
2-8°C
2-8°C
GHS Hazard statements
H315-H319-H335
RTECS
QI9100000
European Hazard Symbols
Irritant Irritant (Xi)
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
German water hazard class
2
Safety Statements
26-36
MSDS Link
Product Information
Empirical Formula (Hill Notation)
C22H24N2O8 · HCl
Purity
≥96.0% (HPLC)
Molecule Details
Biochem/physiol Actions
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.Mode of Resistance: Loss of cell wall permeability.
Molecular Spectra
No Data Available
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References
No Data Available
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