Substance
ID:354553
Names and Identifiers
IUPAC Traditional name
sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
IUPAC name
sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Synonyms
Cefotaxim sodium salt 钠盐Cefotaxime sodium salt 钠盐Cefotaxime sodium saltCefotaxim sodium salt
Registration numbers
EC Number
CAS Number
Beilstein Number
MDL Number
Properties
Safety Information
GHS Hazard statements
H317-H334
Safety Statements
22-36/37
GHS Signal Word
Danger
GHS Precautionary statements
P261-P280-P342+P311
RTECS
XI0250000
MSDS Link
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Storage Temperature
2-8°C
Risk Statements
42/43
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
German water hazard class
2
European Hazard Symbols
Harmful (Xn)Product Information
Impurities
≤5% water
Purity
≥98.0% (TLC)
Empirical Formula (Hill Notation)
C16H16N5NaO7S2
Physical Property
Solubility
H2O: soluble50 mg/mL, clear, light yellow
Molecule Details
Other Notes
Broad spectrum third generation cephalosporin antibiotic.
Biochem/physiol Actions
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Broad spectrum third generation cephalosporin antibiotic.
Biochem/physiol Actions
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data