Substance
ID:354092
Names and Identifiers
Synonyms
Antibiotic X464Helexin CPolyetherin ANigericin sodium saltAntibiotic K178Azalomycin M
IUPAC name
sodium (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl]methyl}-3-methyloxan-2-yl]propanoate
IUPAC Traditional name
sodium (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl]methyl}-3-methyloxan-2-yl]propanoate
Properties
Safety Information
Storage Temperature
2-8°C
MSDS Link
GHS Signal Word
Danger
Packing Group
3
RID/ADR
UN 3462 6.1/PG 3
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Hazard Class
6.1
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
European Hazard Symbols
Toxic (T)Risk Statements
25-36/37/38
Safety Statements
26-36/37/39-45
German water hazard class
3
GHS Hazard statements
H301-H315-H319-H335
GHS Precautionary statements
P261-P301+P310-P305+P351+P338
RTECS
QT6840000
UN Number
3462
Physical Property
Solubility
chloroform: soluble10 mg/mL, clear, colorless
Product Information
Biological Source
from Streptomyces hygroscopicus
Empirical Formula (Hill Notation)
C40H67NaO11
Purity
≥98.0% (TLC)
Molecule Details
Biochem/physiol Actions
Polyether ionophore which disrupts membrane potential and stimulates ATPase activity in mitochondria. Ion selectivity is K+> Rb+≥ Cs+>> Na+.
Other Notes
As ion-selective electrode - an efficient K+-carrier.1,2
As ion-selective electrode - an efficient K+-carrier1,2
Polyether ionophore which disrupts membrane potential and stimulates ATPase activity in mitochondria. Ion selectivity is K+> Rb+≥ Cs+>> Na+.
Other Notes
As ion-selective electrode - an efficient K+-carrier.1,2
As ion-selective electrode - an efficient K+-carrier1,2
Molecular Spectra
No Data Available
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References
No Data Available
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