Substance
ID:353900
Names and Identifiers
Synonyms
Staurosporine from Streptomyces sp.Antibiotic AM-2282
IUPAC Traditional name
(2S,3R,4R,6S)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one
IUPAC name
(2S,3R,4R,6S)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one
Properties
Safety Information
GHS Signal Word
Danger
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
MSDS Link
Storage Temperature
2-8°C
GHS Hazard statements
H340-H350
European Hazard Symbols
Toxic (T)GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Risk Statements
45-46
German water hazard class
3
Safety Statements
53-45
GHS Precautionary statements
P201-P308+P313
Product Information
Empirical Formula (Hill Notation)
C28H26N4O3
Purity
≥95.0% (HPLC)
Molecule Details
Biochem/physiol Actions
Potent inhibitor of phospholipid/calcium-dependent protein kinase. Inhibits the upregulation of VEGF expression in tumor cells.
Potent inhibitor of phospholipid/calcium-dependent protein kinase. Inhibits the upregulation of VEGF expression in tumor cells.
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data