Substance
ID:353574
Names and Identifiers
IUPAC name
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
Synonyms
1-(4-氯苯甲酰基)-5-甲氧基-2-甲基-3-吲哚乙酸Indomethacin吲哚美辛1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid
IUPAC Traditional name
indomethacin
Properties
Product Information
Purity
≥99.0% (TLC)
Empirical Formula (Hill Notation)
C19H16ClNO4
Safety Information
Risk Statements
28
Hazard Class
6.1
Safety Statements
28-36/37-45
RID/ADR
UN 2811 6.1/PG 1
GHS Hazard statements
H300
European Hazard Symbols
Highly toxic (T+)MSDS Link
GHS Precautionary statements
P264-P301+P310
RTECS
NL3500000
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
German water hazard class
3
GHS Signal Word
Danger
UN Number
2811
Packing Group
1
Physical Property
Melting Point
155-162 °C
Solubility
ethanol: soluble50 mg/mL, clear, yellow-green
Molecule Details
Biochem/physiol Actions
Cyclooxygenase (COX) inhibitor that is relatively selective for COX-1.
Other Notes
Blocks prostaglandin biosynthesis.; Topography of prostaglandin H synthase1; Cyclooxygenase inhibitor2
Cyclooxygenase (COX) inhibitor that is relatively selective for COX-1.
Other Notes
Blocks prostaglandin biosynthesis.; Topography of prostaglandin H synthase1; Cyclooxygenase inhibitor2
Molecular Spectra
No Data Available
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References
No Data Available
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