Substance
ID:353353
Names and Identifiers
Synonyms
5-FU2,4-Dihydroxy-5-fluoropyrimidine5-Fluoro-2,4(1H,3H)-pyrimidinedione5-Fluorouracil2,4-二羟基-5-氟嘧啶5-氟脲嘧啶5-氟-2,4(1H,3H)-嘧啶二酮
IUPAC name
5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione
IUPAC Traditional name
fluorouracil
Registration numbers
CAS Number
Beilstein Number
PubChem SID
EC Number
MDL Number
Properties
Physical Property
Melting Point
282-286 °C (dec.)(lit.)
282-286 °C (dec.)
Solubility
H2O: soluble10 mg/mL, clear
Safety Information
MSDS Link
RTECS
YR0350000
RID/ADR
UN 2811 6.1/PG 3
German water hazard class
3
European Hazard Symbols
Harmful (Xn)UN Number
2811
Risk Statements
22
Hazard Class
6.1
Packing Group
3
Product Information
Purity
≥99.0% (HPLC)
Empirical Formula (Hill Notation)
C4H3FN2O2
Molecule Details
Other Notes
Potent antineoplastic agent. Its determination in tissue with microbore HPLC and fluorescence detection1; Metabolised to fluoro-2′-deoxyuridine monophosphate which inhibits DNA synthesis by blocking thymidylate synthetase2
Potent antineoplastic agent. Its determination in tissue with microbore HPLC and fluorescence detection1; Metabolised to fluoro-2′-deoxyuridine monophosphate which inhibits DNA synthesis by blocking thymidylate synthetase2
Molecular Spectra
No Data Available
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References
No Data Available
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