Substance
ID:353121
Names and Identifiers
IUPAC Traditional name
platinum(II) chloride diamine
IUPAC name
dichloroplatinum diamine
Synonyms
顺式-二胺二氯铂顺-二氯二氨基铂(II)顺氯氨铂cis-Diammineplatinum(II) dichloride顺铂Cisplatincis-Platinum(II) diammine dichloridecis-Dichlorodiammine platinum(II)
Properties
Safety Information
GHS Pictograms
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECS
TP2450000
Safety Statements
53-26-39-45
Hazard Class
6.1
GHS Signal Word
Danger
German water hazard class
3
UN Number
3288
GHS Precautionary statements
P201-P264-P280-P301+P310-P305+P351+P338-P308+P313
GHS Hazard statements
H300-H318-H350
European Hazard Symbols
Toxic (T)RID/ADR
UN 3288 6.1/PG 2
Packing Group
2
MSDS Link
Risk Statements
45-25-41
Product Information
Linear Formula
Pt(NH3)2Cl2
Purity
≥96.0% (Pt)
Physical Property
Melting Point
270 °C(lit.)
Molecule Details
Biochem/physiol Actions
Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.
Other Notes
Antitumor compound1; Review (chemistry and properties)2,3
Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.
Other Notes
Antitumor compound1; Review (chemistry and properties)2,3
Molecular Spectra
No Data Available
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References
No Data Available
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