Substance
ID:352913
Names and Identifiers
Synonyms
R-(-)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chlorideO-Acetyl-L-carnitine hydrochlorideALC(R)-3-Acetoxy-4-(trimethylammonio)butyrate hydrochlorideALCAR
IUPAC name
[(2R)-2-(acetyloxy)-3-carboxypropyl]trimethylazanium chloride
IUPAC Traditional name
O-acetylcarnitinium chloride
Properties
Physical Property
Optical Rotation
[α]20/D -29±1°, c = 1% in H2O
Solubility
H2O: soluble0.1 g/mL, clear, colorless
Safety Information
GHS Precautionary statements
P261-P305+P351+P338
German water hazard class
3
European Hazard Symbols
Irritant (Xi)Risk Statements
36/37/38
Safety Statements
26-36
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Signal Word
Warning
GHS Hazard statements
H315-H319-H335
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
MSDS Link
Product Information
Loss on Drying
≤0.5% loss on drying
Purity
≥99.0% (AT)
Empirical Formula (Hill Notation)
C9H17NO4 · HCl
Molecule Details
Other Notes
Transmembrane action potential studies1
Biochem/physiol Actions
Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.
Transmembrane action potential studies1
Biochem/physiol Actions
Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.
Molecular Spectra
No Data Available
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References
No Data Available
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