Substance

ID:352080

Names and Identifiers
IUPAC Traditional name
loratadine
Synonyms
4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl esterLoratadineLoratidine
IUPAC name
ethyl 4-{13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaen-2-ylidene}piperidine-1-carboxylate
Registration numbers
MDL Number
PubChem SID
CAS Number
Properties
Safety Information
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
MSDS Link
Storage Temperature
2-8°C
German water hazard class
2
Product Information
Empirical Formula (Hill Notation)
C22H23N2O2Cl
Purity
≥98% (HPLC)
Physical Property
Solubility
DMSO: soluble50 mg/mL
H2O: insoluble
Apperance
white powder
Pharmacology Properties
Gene Information
human ... CYP3A4(1576), HRH1(3269), KCNH1(3756), KCNH2(3757), PTAFR(5724)rat ... Hrh1(24448)
Molecule Details
Biochem/physiol Actions
Non-sedating histamine H1-receptor antagonist.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. L9664.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Molecular Spectra
No Data Available
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References
No Data Available
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