Substance
ID:351980
Names and Identifiers
IUPAC name
(4S,4aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
IUPAC Traditional name
aureomycin hydrochloride
Synonyms
氯四环素 盐酸盐金霉素 盐酸盐7-Chlorotetracycline hydrochlorideChlortetracycline hydrochloride
Registration numbers
Beilstein Number
EC Number
MDL Number
CAS Number
PubChem SID
Properties
Product Information
Product Line
BioReagent
Impurities
≤3% water
Purity
≥97.0% (AT)
Empirical Formula (Hill Notation)
C22H23ClN2O8 · HCl
Biological Source
from Streptomyces aureofaciens
Suitability
suitable for fluorescence
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
German water hazard class
2
GHS Hazard statements
H315-H319-H335
Risk Statements
36/37/38
Safety Statements
26
European Hazard Symbols
Irritant (Xi)MSDS Link
RTECS
QI7800000
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Signal Word
Warning
GHS Precautionary statements
P261-P305+P351+P338
Storage Temperature
-20°C
Physical Property
Melting Point
210-215 °C (dec.)(lit.)
Fluorescence
λex 392 nm; λem 536 nm in 0.1 M Tris pH 8.0, 10 mM Ca2+
Molecule Details
Application
Cell-permeable fluorescent probe for Ca2+ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ.
Biochem/physiol Actions
Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens.Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-positive. Less active against Gram-negative bacteria than tetracycline.Mode of Resistance: Loss of cell wall permeability.
Quality
Recommended for fluorescent studies of calcium signaling in cells or tissues.
Cell-permeable fluorescent probe for Ca2+ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ.
Biochem/physiol Actions
Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens.Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-positive. Less active against Gram-negative bacteria than tetracycline.Mode of Resistance: Loss of cell wall permeability.
Quality
Recommended for fluorescent studies of calcium signaling in cells or tissues.
Molecular Spectra
No Data Available
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References
No Data Available
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