Substance
ID:351890
Names and Identifiers
IUPAC name
sodium (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
IUPAC Traditional name
sodium cloxacillin(1-)
Synonyms
Cloxacillin sodium salt
Registration numbers
EC Number
CAS Number
MDL Number
Beilstein Number
PubChem SID
Properties
Product Information
Impurities
≤5% water
Purity
≥97.0% (HPLC)
Empirical Formula (Hill Notation)
C19H17ClN3NaO5S
Safety Information
RTECS
XH8750000
Storage Temperature
2-8°C
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
MSDS Link
German water hazard class
2
Physical Property
Solubility
H2O: soluble50 mg/mL, clear, colorless
Molecule Details
Biochem/physiol Actions
Cloxacillin interferes with the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins. This inhibits the necessary cross-linking and leads to autolysis of the bacteria by autolysins.
Application
Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is used against staphylococci that produce β-lactamase. It is used to study the role of pH in antibiotic effectiveness1 and how oxgall, acid, and hydrogen peroxide stress effects the susceptibility of Bifidobacteria2.
Cloxacillin interferes with the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins. This inhibits the necessary cross-linking and leads to autolysis of the bacteria by autolysins.
Application
Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is used against staphylococci that produce β-lactamase. It is used to study the role of pH in antibiotic effectiveness1 and how oxgall, acid, and hydrogen peroxide stress effects the susceptibility of Bifidobacteria2.
Molecular Spectra
No Data Available
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References
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