Substance
ID:351714
Names and Identifiers
IUPAC name
guanidine hydrochloride
Synonyms
Guanidinium chlorideAminomethanamidine hydrochlorideAminoformamidine hydrochloride亚氨脲 盐酸盐Guanidine hydrochloride胍 盐酸盐盐酸胍亚氨基脲 盐酸盐
IUPAC Traditional name
guanidine hydrochloride
Registration numbers
CAS Number
EC Number
Beilstein Number
MDL Number
PubChem SID
Properties
Product Information
Antion Traces
sulfate (SO42-): ≤50 mg/kg
Cation Traces
Cu: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Zn: ≤5 mg/kg
Bi: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Mg: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Al: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
As: ≤0.1 mg/kg
Sr: ≤5 mg/kg
Ba: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Impurities
insoluble matter, passes filter test
Loss on Drying
≤0.05% loss on drying, 20 °C (HV)
Ignition Residue
≤0.05% (as SO4)
Linear Formula
NH2C(=NH)NH2 · HCl
Product Line
BioUltra
λ
6 M in H2O
Purity
≥99.5% (AT)
Physical Property
pH
4.5-6.0 (25 °C, 6 M in H2O)
Melting Point
180-185 °C(lit.)
Absorption Wavelength
λ: 260 nm Amax: 0.03
λ: 280 nm Amax: 0.02
Solubility
H2O: soluble6 M at 20 °C, clear, colorless
Safety Information
GHS Hazard statements
H302-H315-H319
European Hazard Symbols
Harmful (Xn)Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements
P305+P351+P338
MSDS Link
German water hazard class
2
Safety Statements
22
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Signal Word
Warning
Risk Statements
22-36/38
Molecule Details
Application
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Other Notes
In the extraction and fractionation by cesium sulfate density gradient centrifugation of bovine nasal cartilage proteoglycan1; Induces subunit dissociation and unfolding of bovine liver glutamate dehydrogenase2; Dissociation of apolipoproteins of insect lipophorin3; Denaturation curve4.
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Other Notes
In the extraction and fractionation by cesium sulfate density gradient centrifugation of bovine nasal cartilage proteoglycan1; Induces subunit dissociation and unfolding of bovine liver glutamate dehydrogenase2; Dissociation of apolipoproteins of insect lipophorin3; Denaturation curve4.
Molecular Spectra
No Data Available
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References
No Data Available
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