Substance
ID:351713
Names and Identifiers
IUPAC name
guanidine hydrochloride
Synonyms
Guanidinium chlorideAminomethanamidine hydrochlorideAminoformamidine hydrochloride亚氨脲 盐酸盐Guanidine hydrochloride胍 盐酸盐盐酸胍亚氨基脲 盐酸盐
IUPAC Traditional name
guanidine hydrochloride
Registration numbers
CAS Number
EC Number
Beilstein Number
MDL Number
PubChem SID
Properties
Product Information
Cation Traces
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Pb: ≤5 mg/kg
Fe: ≤5 mg/kg
Cr: ≤5 mg/kg
K: ≤50 mg/kg
Ca: ≤10 mg/kg
Zn: ≤5 mg/kg
Ni: ≤5 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cu: ≤5 mg/kg
Mg: ≤5 mg/kg
Linear Formula
NH2C(=NH)NH2 · HCl
Antion Traces
sulfate (SO42-): ≤50 mg/kg
Grade
for analytical purposes
Ignition Residue
≤0.2% (as SO4)
Loss on Drying
≤0.5% loss on drying, 20 °C (HV)
Purity
≥99.0% (AT)
Safety Information
GHS Precautionary statements
P305+P351+P338
German water hazard class
2
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
MSDS Link
Safety Statements
22
GHS Hazard statements
H302-H315-H319
European Hazard Symbols
Harmful (Xn)Risk Statements
22-36/38
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Signal Word
Warning
Physical Property
Melting Point
180-185 °C(lit.)
Solubility
H2O: soluble6 M at 20 °C, clear, colorless
Molecule Details
Application
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Molecular Spectra
No Data Available
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References
No Data Available
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