Substance
ID:351651
Names and Identifiers
IUPAC name
2-[bis(2-hydroxyethyl)amino]acetic acid
IUPAC Traditional name
bicine
Synonyms
N,N-双(2-羟乙基)甘氨酸BICINEN,N-Bis(2-hydroxyethyl)glycine
Registration numbers
EC Number
MDL Number
CAS Number
Beilstein Number
PubChem SID
Properties
Product Information
Impurities
insoluble matter, passes filter test
Cation Traces
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Co: ≤5 mg/kg
Ni: ≤5 mg/kg
Al: ≤5 mg/kg
Bi: ≤5 mg/kg
Mg: ≤5 mg/kg
Na: ≤50 mg/kg
Ca: ≤20 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg
K: ≤50 mg/kg
Mo: ≤5 mg/kg
Cd: ≤5 mg/kg
Cr: ≤5 mg/kg
Mn: ≤5 mg/kg
Li: ≤5 mg/kg
Antion Traces
sulfate (SO42-): ≤50 mg/kg
chloride (Cl-): ≤50 mg/kg
λ
1 M in H2O
Useful pH Range
7.6 - 9.0
Loss on Drying
≤0.1% loss on drying, 20 °C (HV)
Purity
≥99.5% (T)
Empirical Formula (Hill Notation)
C6H13NO4
Ignition Residue
≤0.1%
Product Line
BioUltra
Safety Information
MSDS Link
German water hazard class
3
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Physical Property
pH
4.0-5.5 (25 °C, 1 M in H2O)
Absorption Wavelength
λ: 260 nm Amax: 0.070
λ: 280 nm Amax: 0.040
p𝘒ₐ
8.3 (25°C)
Solubility
H2O: soluble1 M at 20 °C, clear, colorless
Molecule Details
Application
Recommended buffer for low temperature biochemical work.1 Used in the preparation of stable substrate solution for serum guanase determination.2 Spacer in plasma protein fractionation with Sephadex by isotachophoresis.3
BICINE can be used to study biological buffers and zwitterionic compounds. N,N-Bis(2-hydroxyethyl)glycine has been used in a study that characterized refined crystal structures of human Ca2+/Zn2+-binding S100A3 protein. N,N-Bis(2-hydroxyethyl)glycine has also been used in a study to inform F1 antigen assembly.
Recommended buffer for low temperature biochemical work.1 Used in the preparation of stable substrate solution for serum guanase determination.2 Spacer in plasma protein fractionation with Sephadex by isotachophoresis.3
BICINE can be used to study biological buffers and zwitterionic compounds. N,N-Bis(2-hydroxyethyl)glycine has been used in a study that characterized refined crystal structures of human Ca2+/Zn2+-binding S100A3 protein. N,N-Bis(2-hydroxyethyl)glycine has also been used in a study to inform F1 antigen assembly.
Molecular Spectra
No Data Available
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References
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