Substance
ID:351477
Names and Identifiers
IUPAC name
5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2,4,6,11(16),12,14-heptaen-9-one
IUPAC Traditional name
coumestrol
Synonyms
Coumestrol7,12-Dihydroxycoumestan
Registration numbers
CAS Number
EC Number
PubChem SID
Beilstein Number
MDL Number
Properties
Physical Property
Melting Point
≥350 °C(lit.)
Solubility
DMSO: soluble
Fluorescence
λex 377 nm; λem 437 nm in 0.1 M Tris pH 8.0
Safety Information
GHS Signal Word
Warning
RTECS
DF8077000
GHS Hazard statements
H302-H315-H319-H335
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
MSDS Link
GHS Precautionary statements
P261-P305+P351+P338
German water hazard class
3
Safety Statements
26-36
European Hazard Symbols
Harmful (Xn)Risk Statements
22-36/37/38
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Product Information
Product Line
BioReagent
Empirical Formula (Hill Notation)
C15H8O5
Purity
≥97.5% (HPLC)
Suitability
suitable for fluorescence
Pharmacology Properties
Gene Information
human ... ESR1(2099), ESR2(2100)mouse ... Esr1(13982)rat ... Ar(24208)
Molecule Details
Biochem/physiol Actions
Coumestrol has anti-estrogenic actions in the brain and pituitary, mediated through estrogen receptor-α.1
Coumestrol has anti-estrogenic actions in the brain and pituitary, mediated through estrogen receptor-α.1
Molecular Spectra
No Data Available
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References
No Data Available
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