Substance
ID:351435
Names and Identifiers
IUPAC name
5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2,4,6,11(16),12,14-heptaen-9-one
IUPAC Traditional name
coumestrol
Synonyms
Coumestrol7,12-Dihydroxycoumestan
Registration numbers
CAS Number
EC Number
Beilstein Number
MDL Number
PubChem SID
Properties
Pharmacology Properties
Gene Information
human ... ESR1(2099), ESR2(2100)mouse ... Esr1(13982)rat ... Ar(24208)
Safety Information
GHS Hazard statements
H302-H315-H319-H335
Safety Statements
26-36
RTECS
DF8077000
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements
P261-P305+P351+P338
GHS Signal Word
Warning
European Hazard Symbols
Harmful (Xn)Risk Statements
22-36/37/38
MSDS Link
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
German water hazard class
3
Product Information
Impurities
≤10.0% water
Purity
≥95.0% (HPLC)
Empirical Formula (Hill Notation)
C15H8O5
Physical Property
Melting Point
≥350 °C(lit.)
Molecule Details
Biochem/physiol Actions
Coumestrol has anti-estrogenic actions in the brain and pituitary, mediated through estrogen receptor-α.1
Coumestrol has anti-estrogenic actions in the brain and pituitary, mediated through estrogen receptor-α.1
Molecular Spectra
No Data Available
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References
No Data Available
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