Substance
ID:351233
Names and Identifiers
IUPAC Traditional name
levofloxacin
IUPAC name
(2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
Synonyms
(-)-OfloxacinLevofloxacin
Registration numbers
Beilstein Number
PubChem SID
MDL Number
CAS Number
Properties
Safety Information
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Hazard statements
H302-H317-H334-H361d-H362
Safety Statements
26-36/37/39
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Signal Word
Danger
MSDS Link
RTECS
UU8815550
Risk Statements
63-22-42/43-64
GHS Precautionary statements
P261-P263-P280-P342+P311
European Hazard Symbols
Harmful (Xn)German water hazard class
3
Pharmacology Properties
Gene Information
human ... KCNH1(3756)
Product Information
Empirical Formula (Hill Notation)
C18H20FN3O4
Purity
≥98.0% (HPLC)
Molecule Details
Other Notes
Antibiotic against bacterial respiratory tract infections5,6
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 28266.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Application
Levofloxacin is a broad-spectrum antibiotic used in pharmacokinetic 1, antibiotic resistance 2 , and resistance prevention 3studies.
Biochem/physiol Actions
Levofloxacin is active against Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase (type II topoisomerase) and topoisomerase IV, 4 thereby inhibiting cell division.
Antibiotic against bacterial respiratory tract infections5,6
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 28266.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Application
Levofloxacin is a broad-spectrum antibiotic used in pharmacokinetic 1, antibiotic resistance 2 , and resistance prevention 3studies.
Biochem/physiol Actions
Levofloxacin is active against Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase (type II topoisomerase) and topoisomerase IV, 4 thereby inhibiting cell division.
Molecular Spectra
No Data Available
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References
No Data Available
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