Substance
ID:351232
Names and Identifiers
IUPAC Traditional name
sparfloxacin
IUPAC name
5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Synonyms
司帕沙星5-氨基-1-环丙基-7-(顺式-3,5-二甲基-1-哌嗪基)-6,8-二氟-1,4-二氢-4-氧代-3-喹啉羧酸5-Amino-1-cyclohexyl-7-(cis-3,5-dimethylpiperazino)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acidSparfloxacin
Registration numbers
Beilstein Number
MDL Number
CAS Number
PubChem SID
Properties
Safety Information
GHS Signal Word
Warning
RTECS
VB1986500
Safety Statements
26-36
GHS Precautionary statements
P261-P305+P351+P338
German water hazard class
2
Risk Statements
36/37/38
GHS Hazard statements
H315-H319-H335
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
European Hazard Symbols
Irritant (Xi)MSDS Link
Product Information
Empirical Formula (Hill Notation)
C19H22F2N4O3
Purity
≥98.0% (HPLC)
Pharmacology Properties
Gene Information
human ... KCNH1(3756), TOP2A(7153)
Molecule Details
Biochem/physiol Actions
Inhibits bacterial DNA gyrase (topoisomerase II) and/or topoisomerase IV. Used to modulate (inhibit) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent) DNA supercoiling, and chromosome fragmentation.
Other Notes
Antibacterial agents against respiratory tract infections2
Application
Sparfoxacin is a fluoroquinolone antibiotic used to study antimicrobial activity against mycobacteria and respiratory tract infections 1.
Inhibits bacterial DNA gyrase (topoisomerase II) and/or topoisomerase IV. Used to modulate (inhibit) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent) DNA supercoiling, and chromosome fragmentation.
Other Notes
Antibacterial agents against respiratory tract infections2
Application
Sparfoxacin is a fluoroquinolone antibiotic used to study antimicrobial activity against mycobacteria and respiratory tract infections 1.
Molecular Spectra
No Data Available
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References
No Data Available
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