Substance
ID:351216
Names and Identifiers
IUPAC Traditional name
N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
IUPAC name
N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
Synonyms
辣椒碱Capsaicin8-甲基-N-香草基-反-6-壬烯酰胺8-Methyl-N-vanillyl-trans-6-nonenamide
Registration numbers
EC Number
CAS Number
Beilstein Number
MDL Number
PubChem SID
Properties
Physical Property
Flash Point
113 °C
235.4 °F
Melting Point
62-65 °C(lit.)
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
GHS Signal Word
Danger
European Hazard Symbols
Toxic (T)MSDS Link
Hazard Class
6.1
GHS Precautionary statements
P261-P280-P301+P310-P305+P351+P338-P342+P311
German water hazard class
3
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RTECS
RA8530000
Packing Group
2
GHS Hazard statements
H301-H315-H317-H318-H334-H335
RID/ADR
UN 2811 6.1/PG 2
Safety Statements
22-26-28-36/39-45
UN Number
2811
Risk Statements
25-37/38-41-42/43
Product Information
Compostion
dihydrocapsaicin, 35%
capsaicin, 65%
Grade
natural
Linear Formula
(CH3)2CHCH=CH(CH2)4CONHCH2C6H3-4-(OH)-3-(OCH3)
Pharmacology Properties
Gene Information
human ... CYP1A2(1544), TRPV1(7442)rat ... Trpv1(83810), Trpv4(66026)
Molecule Details
Packaging
1 g in glass bottle
250 mg in glass bottle
Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
1 g in glass bottle
250 mg in glass bottle
Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
Molecular Spectra
No Data Available
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References
No Data Available
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