Substance
ID:351213
Names and Identifiers
IUPAC Traditional name
turkey rhubarb
IUPAC name
1,8-dihydroxy-3-methyl-9,10-dihydroanthracene-9,10-dione
Synonyms
1,8-Dihydroxy-3-methylanthraquinoneChrysophanic acid
Registration numbers
CAS Number
EC Number
PubChem SID
MDL Number
Beilstein Number
Properties
Pharmacology Properties
Gene Information
human ... ELA2(1991)
Safety Information
GHS Signal Word
Warning
German water hazard class
3
MSDS Link
GHS Hazard statements
H315-H319
GHS Precautionary statements
P305+P351+P338
Safety Statements
26
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
European Hazard Symbols
Irritant (Xi)Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
36/38
RTECS
CB6725000
Product Information
Empirical Formula (Hill Notation)
C15H10O4
Purity
98%
Molecule Details
Packaging
1 g in glass bottle
50 mg in glass bottle
Application
Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells 1. It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro 2.
Biochem/physiol Actions
Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway 1. Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus 2.
1 g in glass bottle
50 mg in glass bottle
Application
Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells 1. It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro 2.
Biochem/physiol Actions
Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway 1. Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus 2.
Molecular Spectra
No Data Available
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References
No Data Available
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