Substance
ID:351110
Names and Identifiers
IUPAC Traditional name
mitamycin
IUPAC name
[(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
Synonyms
Mitomycin C from Streptomyces caespitosus丝裂霉素 C 来源于头状链霉菌
Registration numbers
MDL Number
Beilstein Number
CAS Number
EC Number
PubChem SID
Properties
Product Information
Empirical Formula (Hill Notation)
C15H18N4O5
Purity
≥970 μg/mg (USP XXIV)
Safety Information
GHS Hazard statements
H300-H351
RID/ADR
UN 3462 6.1/PG 2
German water hazard class
3
Storage Temperature
2-8°C
Packing Group
2
GHS Signal Word
Danger
MSDS Link
GHS Precautionary statements
P264-P281-P301+P310
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Hazard Class
6.1
European Hazard Symbols
Toxic (T)RTECS
CN0700000
UN Number
3462
Safety Statements
28-36/37-45
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Risk Statements
25-40
Molecule Details
Application
Used as a sequence specific (5′-CpG-3′) DNA crosslinking (alkylation) agent.
Biochem/physiol Actions
Inhibitor of DNA synthesis, nuclear division, and cancer cells. Antibacterial to gram positive, gram negative, acid-fast bacilli.
Other Notes
NaCl free
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Used as a sequence specific (5′-CpG-3′) DNA crosslinking (alkylation) agent.
Biochem/physiol Actions
Inhibitor of DNA synthesis, nuclear division, and cancer cells. Antibacterial to gram positive, gram negative, acid-fast bacilli.
Other Notes
NaCl free
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Molecular Spectra
No Data Available
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References
No Data Available
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