Substance
ID:350677
Names and Identifiers
IUPAC Traditional name
birthwort
IUPAC name
6-methoxy-9-nitro-14,16-dioxatetracyclo[8.7.0.02,7.013,17]heptadeca-1(17),2,4,6,8,10,12-heptaene-11-carboxylic acid
Synonyms
TR 1736Aristolochic acid I
Properties
Safety Information
GHS Precautionary statements
P301+P310
German water hazard class
3
RID/ADR
UN 1544 6.1/PG 3
Packing Group
3
RTECS
CF3325000
UN Number
1544
GHS Signal Word
Danger
Risk Statements
25
Hazard Class
6.1
European Hazard Symbols
Toxic (T)Safety Statements
7-35-45
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Storage Temperature
2-8°C
MSDS Link
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
GHS Hazard statements
H301
Physical Property
Solubility
ethanol: soluble
DMSO: soluble
Apperance
yellow powder
Product Information
Empirical Formula (Hill Notation)
C17H11NO7
Molecule Details
Biochem/physiol Actions
Potent phospholipase A2 inhibitor, including calcium ionophore-induced phospholipase A2 activity in neutrophils. Kidney tumor initiator in experimental animal model.1
Application
Aristolochic acid I is a potent phospholipase A2 inhibitor. Aristolochic acid I induces tumor formation in rat kidneys and apoptosis in human renal proximal tubular epithelial cells.
Potent phospholipase A2 inhibitor, including calcium ionophore-induced phospholipase A2 activity in neutrophils. Kidney tumor initiator in experimental animal model.1
Application
Aristolochic acid I is a potent phospholipase A2 inhibitor. Aristolochic acid I induces tumor formation in rat kidneys and apoptosis in human renal proximal tubular epithelial cells.
Molecular Spectra
No Data Available
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References
No Data Available
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