Substance
ID:350535
Names and Identifiers
Synonyms
BCNU1,3-Bis(2-chloroethyl)-1-nitrosoureaCarmustine
IUPAC name
1,3-bis(2-chloroethyl)-3-nitrosourea
IUPAC Traditional name
carmustine
Properties
Product Information
Purity
≥98%
Empirical Formula (Hill Notation)
C5H9Cl2N3O2
Safety Information
RTECS
YS2625000
GHS Signal Word
Danger
Storage Temperature
-20°C
UN Number
2811
GHS Precautionary statements
P201-P264-P301+P310-P308+P313
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
MSDS Link
Safety Statements
53-22-36/37/39-45
GHS Hazard statements
H300-H350-H360
European Hazard Symbols
Highly toxic (T+)Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RID/ADR
UN 2811 6.1/PG 2
Risk Statements
45-46-60-61-28
Hazard Class
6.1
Packing Group
2
German water hazard class
3
Physical Property
Melting Point
30 °C(lit.)
Apperance
(Oily liquid to amorphous solid)
Pharmacology Properties
Gene Information
human ... GSR(2936)
Molecule Details
Biochem/physiol Actions
Carmustine is a DNA alkylating agent causing DNA interstrand crosslinks.1 Effective against glioma and other solid tumors.
Carmustine is a DNA alkylating agent causing DNA interstrand crosslinks.1 Effective against glioma and other solid tumors.
Molecular Spectra
No Data Available
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References
No Data Available
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