Substance
ID:350518
Names and Identifiers
IUPAC name
7,12-dimethyltetraphene
IUPAC Traditional name
7,12-dimethylbenz(a)anthracene
Synonyms
9,10-Dimethyl-1,2-benzanthracene1,4-二甲基-2,3-苯并菲9,10-二甲基-1,2-苯并蒽1,4-Dimethyl-2,3-benzophenanthrene7,12-二甲基苯并[a]蒽DMBA7,12-Dimethylbenz[a]anthracene
Registration numbers
EC Number
CAS Number
MDL Number
Beilstein Number
PubChem SID
Properties
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Precautionary statements
P201-P308+P313
Risk Statements
45-22
RTECS
CW3850000
Hazard Class
9
GHS Hazard statements
H302-H350
MSDS Link
German water hazard class
3
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
53-36/37-45
GHS Signal Word
Danger
European Hazard Symbols
Toxic (T)RID/ADR
UN 3077 9/PG 3
UN Number
3077
Packing Group
3
Physical Property
Melting Point
122-123 °C(lit.)
Solubility
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Product Information
Purity
≥95%
Empirical Formula (Hill Notation)
C20H16
Molecule Details
Application
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Biochem/physiol Actions
The oxidation of DMBA by P450 enzymes produces metabolites that form covalent adducts with DNA and the formation within DNA of depurinated abasic sites. It is most commonly used to induce skin or mammary tumors in animals, though it also can induce leukemias and tumors at other sites.
Packaging
1, 5 g in glass bottle
100 mg in glass bottle
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Biochem/physiol Actions
The oxidation of DMBA by P450 enzymes produces metabolites that form covalent adducts with DNA and the formation within DNA of depurinated abasic sites. It is most commonly used to induce skin or mammary tumors in animals, though it also can induce leukemias and tumors at other sites.
Packaging
1, 5 g in glass bottle
100 mg in glass bottle
Molecular Spectra
No Data Available
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References
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