Substance
ID:350494
Names and Identifiers
Synonyms
3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanineT4L-Thyroxine3,3′,5,5″-四碘代-L-甲状腺原氨酸L-甲状腺素3,3′,5,5″-Tetraiodo-L-thyronine3-[4-(4-羟基-3,5-二碘苯氧基)-3,5-二碘苯基]-L-丙氨酸
IUPAC name
(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
IUPAC Traditional name
levothyroxine
Registration numbers
MDL Number
EC Number
Beilstein Number
CAS Number
PubChem SID
Properties
Product Information
Potency
5-50 ng/mL
Linear Formula
HOC6H2(I)2OC6H2(I)2CH2CH(NH2)CO2H
Suitability
suitable for cell culture
Product Line
BioReagent
Physical Property
Melting Point
223 °C (dec.)(lit.)
Apperance
powder
Safety Information
MSDS Link
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS
YP2833500
German water hazard class
3
Pharmacology Properties
Gene Information
human ... TTR(7276)mouse ... Cnr2(12802)rat ... Cnr1(25248)
Molecule Details
Biochem/physiol Actions
L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and, thus, protein synthesis.
Reconstitution
To prepare 20 μg/ml stock solution, dissolve in 50 ml sterile culture medium per mg thyroxine.
Physical form
powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw, solution stable 2-8 °C, 30 days
L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and, thus, protein synthesis.
Reconstitution
To prepare 20 μg/ml stock solution, dissolve in 50 ml sterile culture medium per mg thyroxine.
Physical form
powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw, solution stable 2-8 °C, 30 days
Molecular Spectra
No Data Available
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References
No Data Available
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