Substance
ID:350450
Names and Identifiers
IUPAC name
methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-4-methoxy-4-oxobutanamido]-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate
IUPAC Traditional name
methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-4-methoxy-4-oxobutanamido]-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate
Synonyms
Z-VDVAD-FMKZ-Val-Asp(O-Me)-Val-Ala-Asp(O-Me) fluoromethyl ketone
Registration numbers
MDL Number
Properties
Physical Property
Solubility
DMSO/DMF: soluble20 mM
Apperance
white powder
Safety Information
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature
-20°C
MSDS Link
German water hazard class
3
Product Information
Shipped in
dry ice
Purity
≥90% (TLC)
Linear Formula
C32H46N5O11F
Pharmacology Properties
Gene Information
human ... CASP2(835)mouse ... CASP2(12366)rat ... CASP2(64314)
Molecule Details
Amino Acid Sequence
Z-Val-Asp-OMe-Val-Ala-Asp-OMe-FMK
Biochem/physiol Actions
A cell-permeable inhibitor of caspase-2, which exhibits competitive and irreversible inhibition.
Z-Val-Asp-OMe-Val-Ala-Asp-OMe-FMK
Biochem/physiol Actions
A cell-permeable inhibitor of caspase-2, which exhibits competitive and irreversible inhibition.
Molecular Spectra
No Data Available
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References
No Data Available
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