Substance
ID:350422
Names and Identifiers
Synonyms
3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine hydrochlorideNortriptyline hydrochlorideDesmethylamitriptyline hydrochloride
IUPAC Traditional name
methyl(3-{tricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene}propyl)amine hydrochloride
IUPAC name
methyl(3-{tricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene}propyl)amine hydrochloride
Properties
Safety Information
MSDS Link
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
European Hazard Symbols
Harmful (Xn)Safety Statements
22-36
German water hazard class
3
RTECS
HP0175000
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Signal Word
Warning
GHS Hazard statements
H302
Risk Statements
22
Physical Property
Apperance
white to off-white powder
Solubility
ethanol: soluble100 mg/mL
H2O: soluble
Pharmacology Properties
Gene Information
human ... HTR2A(3356), HTR2B(3357), HTR2C(3358)
Product Information
Purity
≥98% (TLC)
Empirical Formula (Hill Notation)
C19H21N · HCl
Molecule Details
Features and Benefits
The powder is stable at least 5 years at room temperature.
Biochem/physiol Actions
Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter (Ki = 3.4 nM) than the serotonin transporter (Ki = 161 nM). 5-HT2 serotonin receptor antagonist.
The powder is stable at least 5 years at room temperature.
Biochem/physiol Actions
Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter (Ki = 3.4 nM) than the serotonin transporter (Ki = 161 nM). 5-HT2 serotonin receptor antagonist.
Molecular Spectra
No Data Available
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References
No Data Available
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