Substance
ID:350162
Names and Identifiers
IUPAC name
(2S)-2-amino-4-(carbamimidamidooxy)butanoic acid
IUPAC Traditional name
canavanine
Synonyms
L-α-Amino-γ-(guanidinooxy)-n-butyric acidL-刀豆氨酸L-Canavanine
Properties
Safety Information
European Hazard Symbols
Harmful (Xn)GHS Precautionary statements
P280
German water hazard class
3
GHS Hazard statements
H302-H312-H332
Safety Statements
36
MSDS Link
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
20/21/22
RTECS
ES7002000
Storage Temperature
2-8°C
GHS Signal Word
Warning
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Product Information
Biological Source
from Canavalia ensiformis
Empirical Formula (Hill Notation)
C5H12N4O3
Purity
≥98% (TLC)
Physical Property
Apperance
powder
Solubility
H2O: <100 mg/mL
Molecule Details
Biochem/physiol Actions
A naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.
Canavanine is a naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C1625.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
A naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.
Canavanine is a naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C1625.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Molecular Spectra
No Data Available
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References
No Data Available
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