Substance
ID:350012
Names and Identifiers
IUPAC name
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate
IUPAC Traditional name
forskolin
Synonyms
Coleonol7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-oneForskolinColforsin
Registration numbers
CAS Number
MDL Number
EC Number
PubChem SID
Beilstein Number
Properties
Safety Information
GHS Signal Word
Warning
RTECS
QL6150000
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements
P280
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Hazard statements
H312
German water hazard class
3
European Hazard Symbols
Harmful (Xn)MSDS Link
Risk Statements
21
Safety Statements
22-36/37
Product Information
Purity
≥98%
Product Line
BioReagent
Biological Source
from Coleus forskohlii
Grade
for molecular biology
Empirical Formula (Hill Notation)
C22H34O7
Pharmacology Properties
Gene Information
human ... OPRK1(4986), SLC2A10(81031), TNF(7124)
Molecule Details
Frequently Asked Questions
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Analysis Note
Tested for inhibition of interleukin-2 production by Jurkat cells.
Biochem/physiol Actions
Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase.
Live Chat and Frequently Asked Questions are available for this Product.
Analysis Note
Tested for inhibition of interleukin-2 production by Jurkat cells.
Biochem/physiol Actions
Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase.
Molecular Spectra
No Data Available
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References
No Data Available
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