Substance
ID:349953
Names and Identifiers
IUPAC name
4-hydroxyquinoline-2-carboxylic acid
IUPAC Traditional name
kynurenic acid
Synonyms
4-羟基喹啉-2-甲酸4-Hydroxyquinoline-2-carboxylic acidKynurenic acid犬尿喹啉酸
Registration numbers
CAS Number
MDL Number
Beilstein Number
EC Number
PubChem SID
Properties
Safety Information
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
MSDS Link
German water hazard class
3
GHS Signal Word
Warning
European Hazard Symbols
Irritant (Xi)GHS Precautionary statements
P261-P305+P351+P338
GHS Hazard statements
H315-H319-H335
Safety Statements
26-36
Risk Statements
36/37/38
Product Information
Empirical Formula (Hill Notation)
C10H7NO3
Purity
≥98%
Physical Property
Melting Point
275 °C (dec.)(lit.)
Pharmacology Properties
Gene Information
human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143), GRIA3(2892), GRIA4(2893), GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK4(2900), GRIK5(2901), GUCA2A(2980), GUCA2B(2981), NGFR(4804), SLC23A2(9962)rat ... Gria1(50592), Grik1(29559), Grin2a(24409)
Molecule Details
Biochem/physiol Actions
Kynurenic acid is a non-selective antagonist at NMDA and AMPA/kainate receptors; blocks kainic acid neurotoxicity. Kainic acid also blocks nicotinic acetycholine receptors.
Kynurenic acid is a non-selective antagonist at NMDA and AMPA/kainate receptors; blocks kainic acid neurotoxicity. Kainic acid also blocks nicotinic acetycholine receptors.
Molecular Spectra
No Data Available
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References
No Data Available
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