Substance
ID:349811
Names and Identifiers
Synonyms
MTTMethylthiazolyldiphenyl-tetrazolium bromide3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromideThiazolyl Blue Tetrazolium Bromide
IUPAC name
2-(dimethyl-1,3-thiazol-2-yl)-3,5-diphenyl-3H-1,2λ5,3,4-tetrazol-2-ylium bromide
IUPAC Traditional name
2-(dimethyl-1,3-thiazol-2-yl)-3,5-diphenyl-1,2λ5,3,4-tetrazol-2-ylium bromide
Registration numbers
CAS Number
EC Number
Beilstein Number
MDL Number
PubChem SID
Properties
Product Information
Empirical Formula (Hill Notation)
C18H16BrN5S
Purity
98%
Physical Property
Melting Point
195 °C (dec.)(lit.)
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS
XF8060000
GHS Hazard statements
H315-H319-H335-H341
European Hazard Symbols
Harmful (Xn)German water hazard class
3
Safety Statements
26-36/37
GHS Precautionary statements
P261-P281-P305+P351+P338
Risk Statements
36/37/38-68
Storage Temperature
2-8°C
GHS Signal Word
Warning
MSDS Link
Molecule Details
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Packaging
1, 5, 10 g in glass bottle
100, 250, 500 mg in glass bottle
Application
Thiazolyl Blue Tetrazolium Blue (MTT) may be used in measurement of cell proliferation.1,2,3,4,5 MTT produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells. The blue crystals are solubilized with acidified isopropanol and the intensity is measured colorimetrically at 570 nm. MTT has been used as a histochemical/cytochemical reagent6 and for the detection of NAD.7 ADP-linked enzyme systems in tissue cannot be detected with MTT, due to binding of the cation by the cyanide trap used.8 MTT is rapidly reduced to the formazan, which chelates with nickel, copper, and cobalt; the cobalt chelate has been used in oxidative systems.9
Live Chat and Frequently Asked Questions are available for this Product.
Packaging
1, 5, 10 g in glass bottle
100, 250, 500 mg in glass bottle
Application
Thiazolyl Blue Tetrazolium Blue (MTT) may be used in measurement of cell proliferation.1,2,3,4,5 MTT produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells. The blue crystals are solubilized with acidified isopropanol and the intensity is measured colorimetrically at 570 nm. MTT has been used as a histochemical/cytochemical reagent6 and for the detection of NAD.7 ADP-linked enzyme systems in tissue cannot be detected with MTT, due to binding of the cation by the cyanide trap used.8 MTT is rapidly reduced to the formazan, which chelates with nickel, copper, and cobalt; the cobalt chelate has been used in oxidative systems.9
Molecular Spectra
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References
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