Substance
ID:349722
Names and Identifiers
IUPAC name
2-(2-hydroxybenzoyloxy)benzoic acid
IUPAC Traditional name
salina
Synonyms
salicylsalicylic acid2-Hydroxybenzoic acid 2-carboxyphenyl esterdisalicylic acidsalicyloxysalicylic acid2-(2-Hydroxybenzoyl)oxybenzoic acidSalsalate
Properties
Physical Property
Apperance
white to tan powder
Solubility
DMSO: ≥15 mg/mL
Safety Information
GHS Signal Word
Warning
European Hazard Symbols
Nature polluting (N)
Harmful (Xn)Risk Statements
22-50
GHS Precautionary statements
P273
Storage Temperature
room temp
MSDS Link
German water hazard class
3
GHS Pictograms
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Hazard statements
H302-H400
Safety Statements
61
Product Information
Purity
≥98% (HPLC)
Empirical Formula (Hill Notation)
C14H10O5
Molecule Details
Biochem/physiol Actions
Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes.
Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes.
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data