Substance
ID:349558
Names and Identifiers
IUPAC name
5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione
IUPAC Traditional name
rosiglitazone
Synonyms
rosiglitazoneRosiglitazone5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
Properties
Physical Property
Apperance
powder
Solubility
DMSO: ≥10 mg/mL
Product Information
Linear Formula
C18H19N3O3S
Purity
≥98% (HPLC)
≥98% (HPLC)
Safety Information
Molecule Details
Biochem/physiol Actions
Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor. It is antidiabetic, working as an insulin sensitizer by binding to the PPARγ receptors in fat cells and making the cells more responsive to insulin.
Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor. It is antidiabetic, working as an insulin sensitizer by binding to the PPARγ receptors in fat cells and making the cells more responsive to insulin.
Molecular Spectra
No Data Available
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References
No Data Available
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