Substance
ID:349523
Names and Identifiers
IUPAC name
2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
IUPAC Traditional name
2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
Synonyms
2-(2-Chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamidePD184352CI-1040
Properties
Product Information
Empirical Formula (Hill Notation)
C17H14ClF2IN2O2
Purity
≥98% (HPLC)
Physical Property
Apperance
white to tan powder
Solubility
DMSO: ≥30 mg/mL
Safety Information
GHS Hazard statements
H400
German water hazard class
3
GHS Pictograms
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
GHS Signal Word
Warning
European Hazard Symbols
Nature polluting (N)Storage Temperature
room temp
Safety Statements
60-61
Risk Statements
50/53
MSDS Link
GHS Precautionary statements
P273
Molecule Details
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
PD184352 (CI-1040) is a highly selective non-competitive inhibitor of MEK (MKK1; MAPK kinase) and the closely related MKK2. It has anti-cancer activity, suppresses the ERK pathway, and has been used along with other classes of inhibitors to establish embryonic stem cell lines.
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
PD184352 (CI-1040) is a highly selective non-competitive inhibitor of MEK (MKK1; MAPK kinase) and the closely related MKK2. It has anti-cancer activity, suppresses the ERK pathway, and has been used along with other classes of inhibitors to establish embryonic stem cell lines.
Molecular Spectra
No Data Available
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References
No Data Available
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