Substance
ID:349517
Names and Identifiers
IUPAC Traditional name
tegafur
IUPAC name
5-fluoro-1-(oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
Synonyms
TegafurFtorafur5-Fluoro-1-(tetrahydro-2-furyl)uracilTegafur
Properties
Product Information
Purity
≥98% (HPLC)
≥98% (HPLC)
Empirical Formula (Hill Notation)
C8H9FN2O3
Physical Property
Apperance
white to off-white powder
Melting Point
171-173 °C(lit.)
Solubility
DMSO: >50 mg/mL
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS Signal Word
Danger
European Hazard Symbols
Toxic (T)GHS Precautionary statements
P261-P280-P301+P310-P311
MSDS Link
Storage Temperature
room temp
GHS Hazard statements
H301-H311-H331
Safety Statements
22-36/37/39-45
Risk Statements
23/24/25
German water hazard class
3
Molecule Details
Biochem/physiol Actions
Tegafur is a pro-drug of 5-fluorouracil, an antimetabolite used as an antineoplastic agent. It has been used as adjuvant chemotherapy for curatively resected colorectal cancer therapy.
Tegafur is a pro-drug of 5-fluorouracil, an antimetabolite used as an antineoplastic agent. It has been used as adjuvant chemotherapy for curatively resected colorectal cancer therapy.
Molecular Spectra
No Data Available
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References
No Data Available
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