Substance
ID:349499
Names and Identifiers
IUPAC name
(4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-imidazolidine]-2',5'-dione
Synonyms
(+)-(4S)-6-Fluorospiro[chroman-4,4′-imidazolidine]-2′,5′-dioneSorbinil(4S)-6-Fluoro-2,3-dihydro-spiro[4H-1-benzopyran-4,4′-imidazolidine]-2′,5′-dioneCP 45634
IUPAC Traditional name
sorbinil
Properties
Product Information
Empirical Formula (Hill Notation)
C11H9FN2O3
Purity
≥98% (HPLC)
Safety Information
MSDS Link
GHS Hazard statements
H302
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
European Hazard Symbols
Harmful (Xn)Risk Statements
22
GHS Signal Word
Warning
German water hazard class
3
Storage Temperature
2-8°C
Physical Property
Optical Rotation
[α]/D +50 to +60°, c = 1 in methanol
Solubility
DMSO: ≥20 mg/mL
Apperance
white to off-white powder
Molecule Details
Biochem/physiol Actions
Sorbinil is an inhibitor of Aldose Reductase (AR). AR family members AKR1B1 and AKR1B10 have additionally been shown to play roles in inflammation and cancer.
Sorbinil is an inhibitor of Aldose Reductase (AR). AR family members AKR1B1 and AKR1B10 have additionally been shown to play roles in inflammation and cancer.
Molecular Spectra
No Data Available
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References
No Data Available
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