Substance
ID:349373
Names and Identifiers
IUPAC Traditional name
zileuton
IUPAC name
1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea
Synonyms
(±)-N-hydroxy-N-(1-benzo[b]thien-2-ylethyl)ureaZileuton
Properties
Safety Information
GHS Hazard statements
H302-H319
European Hazard Symbols
Harmful (Xn)Storage Temperature
room temp
GHS Signal Word
Warning
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Precautionary statements
P305+P351+P338
Risk Statements
22-36
MSDS Link
Safety Statements
26
German water hazard class
1
Physical Property
Apperance
white to off-white powder
Solubility
DMSO: ≥20 mg/mL at ~60 °C (warm up to 60 C for 5min)
Product Information
Empirical Formula (Hill Notation)
C11H12N2O2S
Purity
≥98% (HPLC)
Molecule Details
Biochem/physiol Actions
Zileuton is an anti-asthmatic, an inhibitor of 5-lipoxygenase; the initial enzyme in the biosynthesis of leukotrienes from arachidonic acid.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. Z4277.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Zileuton is an anti-asthmatic, an inhibitor of 5-lipoxygenase; the initial enzyme in the biosynthesis of leukotrienes from arachidonic acid.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. Z4277.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Molecular Spectra
No Data Available
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References
No Data Available
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