Substance
ID:349324
Names and Identifiers
IUPAC name
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}oxane-3,4-diol
IUPAC Traditional name
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}oxane-3,4-diol
Synonyms
新霉素 溶液Neomycin solution
Registration numbers
PubChem SID
Properties
Product Information
Sterility
sterile-filtered
Suitability
suitable for cell culture
Impurities
endotoxin, tested
Product Line
BioReagent
Safety Information
Storage Temperature
2-8°C
German water hazard class
2
GHS Hazard statements
H317-H334
European Hazard Symbols
Harmful (Xn)Safety Statements
23-36/37-45
MSDS Link
GHS Precautionary statements
P261-P280-P342+P311
Personal Protective Equipment
Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Risk Statements
42/43
GHS Signal Word
Danger
Pharmacology Properties
Gene Information
human ... TERT(7015)
Physical Property
Apperance
liquid
Molecule Details
Application
Broadly used in molecular biology and cell culture as a selection agent for prokaryotic cells that have been transformed using the selectable marker gene (neo). Recommended for use in cell culture applications at 5 ml/L.
Biochem/physiol Actions
Mode of action: binds to the 30S and in some cases the 50S subunit causing miscoding; inhibits initiation and elongation during protein synthesis.Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Caution
Stable at 37 °C for 5 days.
Other Notes
Formulated to contain 10 mg/ml neomycin in 0.9% sodium chloride.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Broadly used in molecular biology and cell culture as a selection agent for prokaryotic cells that have been transformed using the selectable marker gene (neo). Recommended for use in cell culture applications at 5 ml/L.
Biochem/physiol Actions
Mode of action: binds to the 30S and in some cases the 50S subunit causing miscoding; inhibits initiation and elongation during protein synthesis.Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Caution
Stable at 37 °C for 5 days.
Other Notes
Formulated to contain 10 mg/ml neomycin in 0.9% sodium chloride.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Molecular Spectra
No Data Available
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References
No Data Available
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