Substance
ID:349198
Names and Identifiers
IUPAC Traditional name
linezolid
IUPAC name
N-{[(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
Synonyms
U-100766PNU-100766LinezolidN-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide
Properties
Safety Information
GHS Signal Word
Danger
Storage Temperature
room temp
GHS Precautionary statements
P314
MSDS Link
RTECS
AC2720000
German water hazard class
3
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Hazard statements
H372
Physical Property
Apperance
white to off-white powder
Solubility
DMSO: >20 mg/mL
Product Information
Purity
≥98% (HPLC)
Empirical Formula (Hill Notation)
C16H20FN3O4
Pharmacology Properties
Target Organ
Bone
Molecule Details
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Linezolid is an oxazolidinone antimicrobial. It binds to a site on the bacterial 23S ribosomal RNA of the 50S subunit and prevents the formation of a functional 70S initiation complex, thus inhibiting bacterial mRNA translation. Linezolid is also a weak, reversible, nonselective inhibitor of monoamine oxidase.
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Linezolid is an oxazolidinone antimicrobial. It binds to a site on the bacterial 23S ribosomal RNA of the 50S subunit and prevents the formation of a functional 70S initiation complex, thus inhibiting bacterial mRNA translation. Linezolid is also a weak, reversible, nonselective inhibitor of monoamine oxidase.
Molecular Spectra
No Data Available
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References
No Data Available
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