Substance
ID:349121
Names and Identifiers
Synonyms
Dexrazoxane(+)-(S)-4,4′-Propylenedi-2,6-piperazinedioneCardioxaneIcrf-187NSC169780Zinecard(S)-(+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane
IUPAC name
4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione
IUPAC Traditional name
dexrazoxane
Properties
Safety Information
GHS Hazard statements
H315-H319-H335
GHS Precautionary statements
P261-P305+P351+P338
RID/ADR
UN 2811 6.1/PG 3
European Hazard Symbols
Irritant (Xi)Risk Statements
36/37/38
Storage Temperature
room temp
Hazard Class
6.1
Packing Group
3
German water hazard class
3
GHS Signal Word
Warning
MSDS Link
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Safety Statements
26-36
UN Number
2811
Physical Property
Solubility
DMSO: >20 mg/mL
Apperance
white to off-white powder
Product Information
Empirical Formula (Hill Notation)
C11H16N4O4
Purity
≥95% (HPLC)
Molecule Details
Biochem/physiol Actions
Dexrazoxane is a cardioprotective compound against anthracyclines. It functions by inhibiting topoisomerase II without inducing DNA strand breaks. Dexrazoxane is a + enantiomer of razoxane.
Dexrazoxane is a cardioprotective compound against anthracyclines. It functions by inhibiting topoisomerase II without inducing DNA strand breaks. Dexrazoxane is a + enantiomer of razoxane.
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data