Substance

ID:349106

Names and Identifiers
IUPAC name
N-[4-(2-{[2-(4-methanesulfonamidophenoxy)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide
IUPAC Traditional name
N-[4-(2-{[2-(4-methanesulfonamidophenoxy)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide
Synonyms
DofetilideN-[4-[2-[Methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]methanesulfonamideUK-68798
Registration numbers
CAS Number
MDL Number
Properties
Safety Information
European Hazard Symbols
Toxic Toxic (T)
Nature polluting Nature polluting (N)
GHS Pictograms
GHS07
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
MSDS Link
Safety Statements
53-22-36-57
GHS Signal Word
Danger
Storage Temperature
room temp
GHS Hazard statements
H302-H360
German water hazard class
nwg
Risk Statements
61-48/22-51
GHS Precautionary statements
P201-P308+P313
Product Information
Purity
≥98% (HPLC)
Empirical Formula (Hill Notation)
C19H27N3O5S2
Physical Property
Solubility
DMSO: >20 mg/mL
Apperance
white to off-white powder
Molecule Details
Biochem/physiol Actions
Dofetilide is a Class III antiarrhythmic and hERG channel blocker. Dofetilide selectively blocks the rapid component of the delayed rectifier outward potassium current (IKr).
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Molecular Spectra
No Data Available
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References
No Data Available
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