Substance
ID:348890
Names and Identifiers
IUPAC name
2-hexadecanamidoacetic acid
IUPAC Traditional name
N-palmitoyl glycine
Synonyms
PalGlyHexadecanoylaminoacetic acidN-palmitoyl glycine
Properties
Product Information
Purity
≥98% (HPLC)
Empirical Formula (Hill Notation)
C18H35NO3
Safety Information
German water hazard class
2
MSDS Link
Personal Protective Equipment
Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
Storage Temperature
2-8°C
Physical Property
Solubility
DMSO: >10 mg/mL
Apperance
white to off-white solid
Molecule Details
Biochem/physiol Actions
PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated.
PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated.
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data