Substance
ID:348862
Names and Identifiers
IUPAC Traditional name
reversine
IUPAC name
6-N-cyclohexyl-2-N-[4-(morpholin-4-yl)phenyl]-7H-purine-2,6-diamine
Synonyms
2-(4-Morpholinoanilino)-6-cyclohexylaminopurineReversine
Properties
Product Information
Purity
≥98% (HPLC)
Empirical Formula (Hill Notation)
C21H27N7O
Pharmacology Properties
Gene Information
human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)rat ... Adora3(25370)
Physical Property
Solubility
DMSO: soluble7 mg/mL
H2O: insoluble
Apperance
solid
Safety Information
European Hazard Symbols
Harmful (Xn)GHS Signal Word
Warning
Risk Statements
22
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Hazard statements
H302
MSDS Link
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Storage Temperature
2-8°C
German water hazard class
3
Molecule Details
Biochem/physiol Actions
Reversine is a potent, selective human A3 adenosine receptor antagonist with a Ki value of 0.66 μM. Synthetic substituted purine implicated in cellular regeneration; induces differentiated myogenic-lineage-committed cells to become multipotent mesenchymal progenitor cells.
Reversine is a potent, selective human A3 adenosine receptor antagonist with a Ki value of 0.66 μM. Synthetic substituted purine implicated in cellular regeneration; induces differentiated myogenic-lineage-committed cells to become multipotent mesenchymal progenitor cells.
Molecular Spectra
No Data Available
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References
No Data Available
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