Substance
ID:348772
Names and Identifiers
Synonyms
Cryptotanshinone(R)-(-)-1,6,6-Trimethyl-1,2,6,7,8,9-hexahydrophenanthro[1,2-b]furan-10,11-dione
IUPAC name
(14R)-6,6,14-trimethyl-12-oxatetracyclo[8.7.0.02,7.011,15]heptadeca-1(10),2(7),8,11(15)-tetraene-16,17-dione
IUPAC Traditional name
(14R)-6,6,14-trimethyl-12-oxatetracyclo[8.7.0.02,7.011,15]heptadeca-1(10),2(7),8,11(15)-tetraene-16,17-dione
Properties
Physical Property
Optical Rotation
[α]/D -85.0±3.0°, c = 0.1 in chloroform
Safety Information
MSDS Link
GHS Precautionary statements
P273-P301+P310-P501
RTECS
SF8282645
European Hazard Symbols
Toxic (T)
Nature polluting (N)Safety Statements
45-60-61
Storage Temperature
2-8°C
GHS Pictograms
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS Hazard statements
H301-H410
GHS Signal Word
Danger
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
25-50/53
German water hazard class
3
Product Information
Purity
≥90% (HPLC)
Empirical Formula (Hill Notation)
C19H20O3
Molecule Details
Biochem/physiol Actions
Cryptotanshinone is an antibacterial and anti-inflammatory compound originally extracted from the roots of Salvia miltiorrhiaz (danshen). Cryptotanshinone has been found to inhibit HIF activation1 and to inhibit macrophage migration negatively regulate the PI3K pathway.2,3 It has demonstrated activity against several strains of Staphylococcus aureus.4
Cryptotanshinone is an antibacterial and anti-inflammatory compound originally extracted from the roots of Salvia miltiorrhiaz (danshen). Cryptotanshinone has been found to inhibit HIF activation1 and to inhibit macrophage migration negatively regulate the PI3K pathway.2,3 It has demonstrated activity against several strains of Staphylococcus aureus.4
Molecular Spectra
No Data Available
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References
No Data Available
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