Substance
ID:348770
Names and Identifiers
Synonyms
Albendazole sulfoxideAlbendazole oxideRicobendazoleMethyl [5-(propane-1-sulfinyl)-1H-benzoimidazol-2-yl]-carbamate
IUPAC name
methyl N-[5-(propane-1-sulfinyl)-1H-1,3-benzodiazol-2-yl]carbamate
IUPAC Traditional name
(+-)-albendazole sulfoxide
Properties
Safety Information
Risk Statements
22
RTECS
FD1080000
MSDS Link
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Signal Word
Warning
European Hazard Symbols
Harmful (Xn)GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Hazard statements
H302
German water hazard class
3
Product Information
Empirical Formula (Hill Notation)
C12H15N3O3S
Purity
≥98% (HPLC)
Molecule Details
Biochem/physiol Actions
Ricobendazole is a key metabolite of albendazole and acts as an anthelmintic. It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting cell cycle at the G2/M phase.2
Application
Ricobendazole is a methylcarbamate benzimidazole with a broad-spectrum anthelmintic activity. Ricobendazole is a key metabolite of albendazole 1. It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting the cell cycle at the G2/M phase.2
Ricobendazole is a key metabolite of albendazole and acts as an anthelmintic. It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting cell cycle at the G2/M phase.2
Application
Ricobendazole is a methylcarbamate benzimidazole with a broad-spectrum anthelmintic activity. Ricobendazole is a key metabolite of albendazole 1. It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting the cell cycle at the G2/M phase.2
Molecular Spectra
No Data Available
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References
No Data Available
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