Substance
ID:348738
Names and Identifiers
IUPAC name
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
IUPAC Traditional name
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
Synonyms
Sch 16423a,a,a-Trifluoro-2-methyl-4′-nitro-m-lactotoluidide2-HydroxyflutamideHydroxyflutamide2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-propanamideHydroxyniphtholide
Properties
Safety Information
European Hazard Symbols
Irritant (Xi)GHS Hazard statements
H315-H319-H335
Safety Statements
26-36/37/39
Storage Condition
desiccated
Storage Temperature
room temp
GHS Signal Word
Warning
GHS Precautionary statements
P261-P305+P351+P338
RTECS
TX1466250
German water hazard class
3
MSDS Link
Risk Statements
36/37/38
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Product Information
Purity
≥98% (HPLC)
Empirical Formula (Hill Notation)
C11H11F3N2O4
Physical Property
Apperance
white to tan powder
Solubility
DMSO: >10 mg/mL
Molecule Details
Biochem/physiol Actions
Hydroxflutamide is an AR antagonist. Androgen receptors (ARs) are nuclear hormone receptors/transcription factors. Hydroxyflutamide is an androgen antagonist with publications going back to 1981. It is one of a few gold standard AR antagonists; activities of new antagonists are measured against hydroxyflutamide.
Hydroxflutamide is an AR antagonist. Androgen receptors (ARs) are nuclear hormone receptors/transcription factors. Hydroxyflutamide is an androgen antagonist with publications going back to 1981. It is one of a few gold standard AR antagonists; activities of new antagonists are measured against hydroxyflutamide.
Molecular Spectra
No Data Available
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References
No Data Available
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