Substance
ID:348664
Names and Identifiers
IUPAC Traditional name
topiramate
Synonyms
TopamaxMcN 4853RWJ 170212,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamateTopiramate
IUPAC name
[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-6-yl]methyl sulfamate
Properties
Safety Information
GHS Precautionary statements
P261-P305+P351+P338
GHS Signal Word
Warning
RTECS
LS7083000
GHS Hazard statements
H315-H319-H335
MSDS Link
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
36/37/38
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
European Hazard Symbols
Irritant (Xi)Safety Statements
26-36
Storage Temperature
2-8°C
German water hazard class
3
Product Information
Purity
≥98% (HPLC)
Empirical Formula (Hill Notation)
C12H21NO8S
Physical Property
Apperance
white solid
Solubility
DMSO: ~44 mg/mL
Pharmacology Properties
Gene Information
human ... CA1(759), CA2(760), CA4(762), CA5A(763), CA5B(11238), CA9(768)mouse ... Car5a(12352)rat ... Car2(54231), Car4(29242)
Molecule Details
Biochem/physiol Actions
Kainate GluR5 receptor antagonist; anticonvulsant.
Kainate GluR5 receptor antagonist; anticonvulsant.
Molecular Spectra
No Data Available
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References
No Data Available
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